Modern flow cytometric methods allow the simultaneous detection of more than one fluorescent dye, this is termed “Multicolor flow cytometry”.
Thus, multicolor flow cytometry is a technology platform to gather detailed information on specific cells within a mixed population or on different parameters at the single cell level. This is especially relevant to maximize data generation from small or limited samples.
FOCUS Biomarker offers Multicolor Flow Cytometry to analyse immune cell parameters in clinical trials under GLP conditions. Together with our expertise in standardized cell sample generation and transportation as well as GLP-compliant assay development we offer this interesting technology for biomarker determination. This will enhance the assessment of PD aspects in early and late clinical trials with immuno-modulatory or anti-inflammatory drugs.
FOCUS Immunology laboratory is part of the Clinical Research Organisation (CRO) FOCUS-CDD GmbH. FOCUS Immunology provides immunological biomarker services under GLP and non-GLP conditions for the development of novel medicines.
Natural Killer (NK) cells play an important role in anti-viral and anti-tumor immune responses. NK cells appear to be involved in many pathologies and many therapeutic strategies involve the modulation of NK cell activity.
FOCUS Immunology has established state-of-the art protocols for the phenotypic and functional analysis of NK cells.
For further information on our expertise in NK cell biology please contact us at immunology@focus-cdd.com or contact directly our Head of FOCUS Immunology Dr. Eddy Bruyns at eddy.bruyns@focus-cdd.com.
FOCUS Immunology laboratory is part of the Clinical Research Organisation (CRO) FOCUS-CDD GmbH. FOCUS Immunology provides immunological biomarker services under GLP and non-GLP conditions for the development of novel medicines.
Lamina Propria Lymphocytes (LPL) are a dominant cell population in the gut-associated lymphoid system. Apparently, LPL play an important role in keeping the immunological homeostasis at the large resorptive interface between the gut lumen and the interior of the body. LPL dysfunctions are thought to contribute to the pathology of chronic inflammatory bowel diseases.
Together with clinical institutions of the Heidelberg Medical Centre FOCUS Immunology has established processes that allow to use purified LPL for cell biological and mode-of-action studies.
For further information on our expertise and service offer in LPL biology please us at immunology@focus-cdd.com or contact directly our Head of FOCUS Immunology Dr. Eddy Bruyns at eddy.bruyns@focus-cdd.com.
FOCUS Immunology laboratory is part of the Clinical Research Organisation (CRO) FOCUS-CDD GmbH. FOCUS Immunology provides immunological biomarker services under GLP and non-GLP conditions for the development of novel medicines.
Tuesday, March 23, 2010
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