Central testing of immune cell functions in an international multi-center trial
FOCUS used the expertise of its Heidelberg-based subsidiary FOCUS Immunology in an international multi-center clinical trial that required the isolation of immune cells from peripheral blood, their transportation and subsequent testing for cellular functions.
Patients were recruited at medical centers in different countries. FOCUS established a robust and simple protocol for standardized on-site cell preparation and organised the controlled transportation of the cells to the central testing laboratory in Heidelberg.
After appropriate quality control of in-coming samples, isolated immune cells were cultured and tested for various functions including cytokine production and proliferation.
The preparation and implementation of standardized sample generation, sample logistics and testing was completed within 6 weeks.
The studies led to further understanding of patient characteristics and the compound’s mode-of-action.
For further information contact FOCUS’ Head of Immmunology laboratory Dr. Eddy Bruyns via eddy.bruyns@focus-cdd.com or +49 (0) 649 35 124.
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11/05/2009
Immune monitoring, Immunology Studies